تعیین ارزش تشخیصی بیوپسی سوزنی و آسپیراسیون در ضایعات استخوان و بافت نرم

Fine needle aspiration biopsy(FNAB) and core needle biopsy(CNBx) have proved to be accurate and cost-effective techniques for diagnosis of inflammatory and neoplastic lesions at different body sites. However, their applicability in bone and soft tissue pathology is still controversial. In this study, our experience with FNAB and CNBx of musculoskeletal lesions was prospectively investigated to determine the diagnostic values of different closed biopsy techniques in these lesions in contrast to open biopsy. 49 consecutive FNAB and CNBx were reviewed and the results were then compared with conventional biopsy results of bone and soft tissue lesions. FNAB precision was about 61.9% while CNBx distiguished 80% of bone and tissue lesions correctly. Accuracy of both FNAB and CNBx was more than 7% for diagnosing malignant from benign lesions. FNA sensitivity and CNBx specificity for differentiation of malignant from benign lesions was 100%. Although CNBx is an accurate and reliable method for diagnosis of most musculoskeletal lesions, specifically if the site of biopsy is properly chosen, the accuracy and reliability of FNAB is limited to the differential diagnosis of benign and malignant lesions. FNA is a suitable screening test for differentiating malignant from benign musculoskeletal lesions.